Article
The association of COMT genotype with buproprion treatment response in the treatment of major depressive disorder.
Brain and behavior - 1 Jul 2020
Fawver Jay, Flanagan Mindy, Smith Thomas, Drouin Michelle, Mirro Michael
Abstract excerpt
BACKGROUND: Pharmacodynamics and pharmacogenetics are being explored in pharmacological treatment response for major depressive disorder (MDD). Interactions between genotype and treatment response may be dose dependent. In this study, we examined whether MDD patients with Met/Met, Met/Val, and Val/Val COMT genotypes differed in their response to bupropion in terms of depression scores. METHODS: This study...
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