Article
SERRATE interacts with the nuclear exosome targeting (NEXT) complex to degrade primary miRNA precursors in Arabidopsis.
Nucleic acids research - 9 Jul 2020
Bajczyk Mateusz, Lange Heike, Bielewicz Dawid, Szewc Lukasz, Bhat Susheel S, Dolata Jakub, Kuhn Lauriane, Szweykowska-Kulinska Zofia, Gagliardi Dominique, Jarmolowski Artur
Abstract excerpt
SERRATE/ARS2 is a conserved RNA effector protein involved in transcription, processing and export of different types of RNAs. In Arabidopsis, the best-studied function of SERRATE (SE) is to promote miRNA processing. Here, we report that SE interacts with the nuclear exosome targeting (NEXT) complex, comprising the RNA helicase HEN2, the RNA binding protein RBM7 and one of the two zinc-knuckle proteins...
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