Article
Efficacy and safety of glecaprevir/pibrentasvir in patients with HCV genotype 5/6: An integrated analysis of phase 2/3 studies.
Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2020
Yao Betty B, Fredrick Linda M, Schnell Gretja, Kowdley Kris V, Kwo Paul Y, Poordad Fred, Nguyen Kinh, Lee Samuel S, George Christophe, Wong Florence, Gane Edward, Abergel Armand, Spearman Catherine W, Nguyen Tuan, Hung Le Manh, Pham Thuy Tt, Mensa Federico, Asselah Tarik
Abstract excerpt
BACKGROUND & AIMS: Hepatitis C virus (HCV) has high genetic diversity with six major genotypes (GT) GT1-6 and global distribution. HCV GT5 and 6 are rare with < 10 million people infected worldwide. Data on direct-acting antiviral use in these rare HCV genotypes are limited. The study aimed to evaluate the efficacy and safety of glecaprevir/pibrentasvir (G/P) in a pooled analysis of phase 2/3 trials in HCV GT5 or...
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