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Article

A Deregulated Stress Response Underlies Distinct INF2-Associated Disease Profiles.

Journal of the American Society of Nephrology : JASN - 1 Jun 2020

Bayraktar Samet, Nehrig Julian, Menis Ekaterina, Karli Kevser, Janning Annette, Struk Thaddäus, Halbritter Jan, Michgehl Ulf, Krahn Michael P, Schuberth Christian E, Pavenstädt Hermann, Wedlich-Söldner Roland

Abstract excerpt

BACKGROUND: Monogenic diseases provide favorable opportunities to elucidate the molecular mechanisms of disease progression and improve medical diagnostics. However, the complex interplay between genetic and environmental factors in disease etiologies makes it difficult to discern the mechanistic links between different alleles of a single locus and their associated pathophysiologies. Inverted formin 2 (INF2), an...

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Identifiers

PMID: 32444357
DOI: 10.1681/ASN.2019111174
PMCID: PMC7269351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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