Article
SNP dependent modulation of circulating miRNAs from the miR25/93/106 cluster in patients undergoing weight loss.
Gene - 30 Aug 2020
Müller Stephanie, Wallner Stefan, Schmitz Gerd, Loew Thomas, Stempfl Thomas, Möhle Christoph, Strack Christina, Sag Sabine, Baessler Andrea, Fischer Marcus
Abstract excerpt
BACKGROUND: Diet induced weight loss represents an intervention for obesity to prevent associated diseases. However there is considerable inter-individual variation. Single nucleotide polymorphisms (SNPs) and plasma miRNA might be contributing factors. We therefore hypothesized that changes in the miRNA pattern during weight loss depend on the SNP genotype. METHODS: Plasma miRNA profiles from 12 patients were...
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