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Article

Cointegration as a mechanism for the evolution of a KPC-producing multidrug resistance plasmid in Proteus mirabilis

1 Jan 2020

Abstract excerpt

The incidence and transmission of Klebsiella pneumoniae carbapenemase (KPC) producing plasmids have been well documented. However, the evolutionary dynamics of KPC plasmids and their fitness costs are not well characterized. Here, two carbapenemase-producing plasmids from Proteus mirabilis, pT18 and pT211 (both carrying blaKPC-2), were characterized through whole genome sequencing. pT211 is a 24.2 kbp N-type...

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Identifiers

PMID: 32438864
DOI: 10.1080/22221751.2020.1773322

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