Pretreatment resistance mutations and treatment outcomes in adults living with HIV-1: a cohort study in urban Malawi.

doi:10.1186/s12981-020-00282-3

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Article

Pretreatment resistance mutations and treatment outcomes in adults living with HIV-1: a cohort study in urban Malawi.

AIDS research and therapy - 20 May 2020

Neuhann F, de Forest A, Heger E, Nhlema A, Scheller C, Kaiser R, Steffen H M, Tweya H, Fätkenheuer G, Phiri S

Abstract excerpt

BACKGROUND: Pre-treatment drug resistance (PDR) among antiretroviral drug-naïve people living with HIV (PLHIV) represents an important indicator for the risk of treatment failure and the spread of drug resistant HIV variants. We assessed the prevalence of PDR and treatment outcomes among adults living with HIV-1 in Lilongwe, Malawi. METHODS: We selected 200 participants at random from the Lighthouse Tenofovir...

Topics

Adult
Anti-HIV Agents
Cohort Studies
Drug Administration Schedule
Drug Resistance, Viral
Female
Genotype
HIV Infections
HIV-1
Humans
Malawi

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation

Prevalence

Treatment Failure

Treatment Outcome

Urban Population

Source

Open in PubMed Open full text

Identifiers

PMID: 32434561
DOI: 10.1186/s12981-020-00282-3
PMCID: PMC7240935

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