Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction

28 Mar 2020

Abstract excerpt

Transportation of key proteins via extracellular vesicles has been recently implicated in various neurodegenerative disorders, including Parkinson's disease, as a new mechanism of disease spreading and a new source of biomarkers. Extracellular vesicles likely to be derived from the brain can be isolated from peripheral blood and have been reported to contain higher levels of α-synuclein (α-syn) in Parkinson's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Extracellular vesicles in disease
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32428221
DOI: 10.1093/brain/awaa110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunctionPMID 32428221Read ↗

A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson’s DiseaseSemantic proximity Read ↗

Challenges associated with using extracellular vesicles as biomarkers in neurodegenerative diseaseSemantic proximity Read ↗

Fluorescence tagged salivary small extracellular vesicles as a nanotool in early diagnosis of Parkinson’s diseaseSemantic proximity Read ↗

α-Synuclein in blood exosomes immunoprecipitated using neuronal and oligodendroglial markers distinguishes Parkinson’s disease from multiple system atrophySemantic proximity Read ↗

The role of exosomes in the diagnosis of Parkinson's diseaseSemantic proximity Read ↗

Biomarker Organization in Circulating Extracellular Vesicles: New Applications in Detecting Neurodegenerative DiseasesSemantic proximity Read ↗

Insights Into the Proteomic Profiling of Extracellular Vesicles for the Identification of Early Biomarkers of NeurodegenerationSemantic proximity Read ↗

Extracellular Vesicles: The Next Generation of Biomarkers and Treatment for Central Nervous System DiseasesSemantic proximity Read ↗

Analysis of α-Synuclein in Exosomes.Semantic proximity Read ↗

Extracellular vesicles from bodily fluids for the accurate diagnosis of Parkinson’s disease and related disorders: A systematic review and meta-analysisSemantic proximity Read ↗

Extracellular Interactions of Alpha-Synuclein in Multiple System AtrophySemantic proximity Read ↗

Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.