Article
Gut microbiota and metabolites in the pathogenesis of endocrine disease.
Biochemical Society transactions - 30 Jun 2020
Fenneman Aline C, Rampanelli Elena, Yin Yue S, Ames Jesse, Blaser Martin J, Fliers Eric, Nieuwdorp Max
Abstract excerpt
Type 1 diabetes (T1D) and Hashimoto's thyroiditis (HT) are the two most common autoimmune endocrine diseases that have rising global incidence. These diseases are caused by the immune-mediated destruction of hormone-producing endocrine cells, pancreatic beta cells and thyroid follicular cells, respectively. Both genetic predisposition and environmental factors govern the onset of T1D and HT. Recent evidence...
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