Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

Cell - 11 Jun 2020

Casanova Jean-Laurent, Su Helen C

Abstract excerpt

SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers-individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease-present a unique opportunity to reveal human genetic determinants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Betacoronavirus
Share to Coronavirus Infections
Share to Disease Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Diseases, Inborn

Share to Infections

Share to Pandemics

Share to Pneumonia, Viral

Share to SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 32405102
DOI: 10.1016/j.cell.2020.05.016
PMCID: PMC7218368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.PMID 32405102Read ↗

Host genomics of SARS-CoV-2 infectionSemantic proximity Read ↗

Understanding SARS-CoV-2: Genetic Diversity, Transmission and Cure in HumanSemantic proximity Read ↗

Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19.Semantic proximity Read ↗

COVID-19 pandemic: Insights into genetic susceptibility to SARS-CoV-2 and host genes implications on virus spread, disease severity and outcomes.Semantic proximity Read ↗

A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection.Semantic proximity Read ↗

The seven enigmas of SARS-CoV-2: From the past to the futureSemantic proximity Read ↗

The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity.Semantic proximity Read ↗

Genetic Variants of SARS-CoV-2: What Do We Know So Far?Semantic proximity Read ↗

Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification.Semantic proximity Read ↗

Systematic assessment of COVID-19 host genetics using whole genome sequencing data.Semantic proximity Read ↗

Genetic Variants of SARS-CoV-2-What Do They Mean?Semantic proximity Read ↗

Genetic variation in SARS-CoV-2 may explain variable severity of COVID-19Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.