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Article

Serum neurofilament light chain is a useful biomarker in pediatric multiple sclerosis

14 May 2020

Abstract excerpt

OBJECTIVE: To investigate serum neurofilament light chain (sNfL) as a potential biomarker for disease activity and treatment response in pediatric patients with multiple sclerosis (MS). METHODS: In this retrospective cohort study, sNfL levels were measured in a pediatric MS cohort (n = 55, follow-up 12-105 months) and in a non-neurologic pediatric control cohort (n = 301) using a high-sensitivity single-molecule...

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PMID: 32404429
DOI: 10.1212/nxi.0000000000000749

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