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Genomic Strategies Toward Identification of Novel Therapeutic Targets.

Handbook of experimental pharmacology - 1 Jan 2022

Kessler Thorsten, Schunkert Heribert

Abstract excerpt

Coronary artery disease, myocardial infarction, and secondary damages of the myocardium in the form of ischemic heart disease remain major causes of death in Western countries. Beyond traditional risk factors such as smoking, hypertension, dyslipidemia, or diabetes, a positive family history is known to increase risk. The genetic factors underlying this observation remained unknown for decades until genetic...

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PMID: 32399778
DOI: 10.1007/164_2020_360

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