Article
Increase of mtDNA number and its mutant copies in rat brain after exposure to 150 MeV protons.
Molecular biology reports - 1 Jun 2020
Abdullaev Serazhutdin, Bulanova Tatiana, Timoshenko Gennady, Gaziev Azhub I
Abstract excerpt
Proton beam therapy is widely used for treating brain tumor. Despite the efficacy of treatment, the use of this therapy has met some limitations associated with possible damage to normal brain tissues located beyond the tumor site. In this context, the exploration of the harmful effects of protons on the normal brain tissues is of particular interest. We have investigated changes in the total mitochondrial DNA...
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