Article
Impaired oocyte maturation and ovulation in membrane progestin receptor (mPR) knockouts in zebrafish.
Molecular and cellular endocrinology - 1 Jul 2020
Wu Xin-Jun, Liu Dong-Teng, Chen Shixi, Hong Wanshu, Zhu Yong
Abstract excerpt
Accumulating evidence suggest that membrane progestin receptor α (mPRα) is the membrane receptor mediating nongenomic progestin signaling that induces oocyte maturation in teleost. However, the involvement of other members of mPR family in oocyte maturation is still unclear. In this study, we found impaired oocyte maturation in zebrafish lacking mPRα1, mPRα2, mPRβ, or mPRγ2. In contrast, no difference was...
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