Article
[Genetic analysis and targeted therapy for acute myeloid leukemia].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2020
Yamaguchi Hiroki
Abstract excerpt
Several chromosomal abnormalities and gene mutations involved in the onset and recurrence of acute myeloid leukemia (AML) were discovered with the recent progress of genome analysis technology. The founding not only have clinical application as prognostic factors and minimal residual disease markers but also contribute to the novel molecular-targeted drug development. Many new drugs such as first-generation FLT3...
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