Article
[Gilteritinib for pediatric FLT3 internal tandem duplication-positive recurrent acute myeloid leukemia].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2020
Fukuoka Kohei, Tsumura Yusuke, Noguchi Jun, Sugawa Masahiro, Takaki Torataro, Hiraki Takamasa, Inoue Kyohei, Mitani Yuichi, Tomita Osamu, Oshima Koichi, Yanagi Masato, Isobe Kiyotaka, Mori Makiko, Arakawa Yuki, Koh Katsuyoshi
Abstract excerpt
Gilteritinib is an FMS-like tyrosine kinase 3 (FLT3) inhibitor that has shown efficacy in patients with refractory or recurrent adult acute myeloid leukemia (AML) with FLT3 mutations. However, there are limited data for pediatric patients treated with this drug. Herein, we report the clinical courses of two children with FLT3-mutated recurrent AML who received gilteritinib. Case 1: An 11-year-old boy with...
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