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Article

Successful treatment with gilteritinib for isolated extramedullary relapse of acute myeloid leukemia with FLT3-ITD mutation after allogeneic stem cell transplantation.

International journal of hematology - 1 Aug 2020

Kida Michiko, Kuroda Yoshiaki, Kido Miki, Chishaki Ren, Kuraoka Kazuya, Ito Takuo

Abstract excerpt

Acute myeloid leukemia (AML) harboring Fms-like tyrosine kinase 3 (FLT3) internal tandem duplication (ITD) mutation is associated with shorter remission and higher relapse risk. Several FLT3 inhibitors have been used in clinical trials, but their efficacy in extramedullary disease remains unclear. In the present case, a 56-year-old man was diagnosed with FLT3-ITD mutated AML. Due to bone marrow relapse during...

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Identifiers

PMID: 32170661
DOI: 10.1007/s12185-020-02855-4

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