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Article

Prognostic implications of pathogenic truncating variants in the TTN gene.

International journal of cardiology - 1 Oct 2020

Peña-Peña Maria Luisa, Ochoa Juan Pablo, Barriales-Villa Roberto, Cicerchia Marcos, Palomino-Doza Julián, Salazar-Mendiguchía Joel, Lamounier Arsonval, Trujillo Juan Pablo, Garcia-Giustiniani Diego, Fernandez Xusto, Ortiz-Genga Martin, Monserrat Lorenzo, Crespo-Leiro Maria Generosa

Abstract excerpt

INTRODUCTION AND OBJECTIVES: TTN gene truncating variants (TTNtv) are a frequent cause of dilated cardiomyopathy (DCM). However, there are discrepant data on the associated prognosis. Our objectives were to describe the prevalence of TTNtv in our cohort and to compare the clinical course with that described in the literature. METHODS: We included patients with DCM and genetic testing performed using...

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Identifiers

PMID: 32371228
DOI: 10.1016/j.ijcard.2020.04.086

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