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Article

Low mutation rate in the TTN gene in paediatric patients with dilated cardiomyopathy - a pilot study.

Scientific reports - 11 Nov 2019

Zaklyazminskaya Elena, Mikhailov Vadim, Bukaeva Anna, Kotlukova Natalia, Povolotskaya Inna, Kaimonov Vladimir, Dombrovskaya Anna, Dzemeshkevich Sergey

Abstract excerpt

Idiopathic dilated cardiomyopathy (DCM) is a common cardiomyopathy with the prevalence of 1:250, and at least one-third of all the cases are inherited. Mutations in the TTN gene are considered as the most frequent cause of inherited DCM and cover 10-30% of the cases. The studies were mainly focused on the adult or mixed age group of patients with DCM. The mutation rate in the TTN gene, the characteristics of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31712709
DOI: 10.1038/s41598-019-52911-1
PMCID: PMC6848193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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