Article
Frequency of HLA Class I and Class II Alleles in Patients with CVID from Turkey.
Immunological investigations - 1 May 2021
Ozbek Begum, Tan Cagman, Yaz Ismail, Kosukcu Can, Esenboga Saliha, Cetinkaya Pınar Gur, Cagdas Deniz, Tezcan Ilhan
Abstract excerpt
BACKGROUND: Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency. Certain gene loci are pointed out in several studies in CVID patients. Until now, monogenic defects have been identified in only 2-10% of CVID patients; therefore, association of the disease with HLA alleles may be important for elucidating immunological and genetic mechanisms behind CVID. The aim of this...
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