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Article

Functional Fibrinolysis Assays Reveal Different Mechanisms underlying Plasminogen Dysfunction in Ligneous Conjunctivitis.

Thrombosis and haemostasis - 1 May 2020

Bourrienne Marie-Charlotte, Loyau Stéphane, Faille Dorothée, de Raucourt Emmanuelle, de Mazancourt Philippe, Ho-Tin-Noé Benoît, Gabison Eric, Ajzenberg Nadine

Abstract excerpt

BACKGROUND: Ligneous conjunctivitis (LC) is a rare disorder associated with plasminogen deficiency characterized by chronic fibrin deposits in the eyelids. All patients with plasminogen deficiency do not develop LC, whose underlying mechanisms remain unknown. OBJECTIVE: We investigated whether fibrinolytic activity was correlated with phenotype and/or genotype in patients suffering from LC and their relatives....

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PMID: 32369847
DOI: 10.1055/s-0040-1709526

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