Article
Long-term follow-up in a pediatric patient with Ligneous Conjunctivitis due to PLG gene mutation in topical plasminogen treatment after successful use of ocular prosthesis for aesthetic rehabilitation: a case report.
Italian journal of pediatrics - 23 Aug 2023
Panfili Filippo Maria, Valente Paola, Ficari Andrea, Cortellessa Fabiana, Vecchio Davide, Gonfiantini Michaela Veronika, Buonuomo Paola Sabrina, Colafati Giovanna Stefania, Agolini Emanuele, Bartuli Maria, Modugno Alessandra Claudia, Macchiaiolo Marina
Abstract excerpt
BACKGROUND: Ligneous Conjunctivitis (LC) is the most common clinical manifestation of Type I Plasminogen deficiency (T1PD; OMIM# 217090), and it is characterized by the formation of pseudomembranes (due to deposition of fibrin) on the conjunctivae leading to progressive vision loss. In past times, patients with LC were treated with surgery, topical anti-inflammatory, cytostatic agents, and systemic...
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