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Generation of allogeneic and xenogeneic functional muscle stem cells for intramuscular transplantation

7 May 2024

Abstract excerpt

Satellite cells, the stem cells of skeletal muscle tissue, hold a remarkable regeneration capacity and therapeutic potential in regenerative medicine. However, low satellite cell yield from autologous or donor-derived muscles hinders the adoption of satellite cell transplantation for the treatment of muscle diseases, including Duchenne muscular dystrophy (DMD). To address this limitation, here we investigated...

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PMID: 38713532
DOI: 10.1172/jci166998

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