Article
HLA-DQ genotype and biochemical characterization of anti-transglutaminase 2 antibodies in patients with type 1 diabetes mellitus in Taiwan.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2020
Lee Yann-Jinn, Ting Wei-Hsin, Yang Yi-Wen, Lin Cheng-Jui, Hsieh Yu-Ting, Huang Chi-Yu, Lo Fu-Sung, Chu Chen-Chung, Lin Chiung-Ling, Lin Wen-Shan, Lai Thung-S
Abstract excerpt
Human Leukocyte Antigen (HLA)-DQ2 and HLA-DQ8 are genetic risk factors for Type 1 Diabetes Mellitus (T1DM) and Celiac disease (CD) in Caucasians, but their association with Taiwanese Han population is unknown. We screened 532 Taiwanese T1DM patients for CD biomarkers including anti-tissue transglutaminase (TGM2), anti-gliadin and anti-neoepitope antibodies (Abs), sequencing DQB1 genotypes, and characterized the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
