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Article

Frequency of HLA-DQB10201/02 and DQB10302 alleles and tissue transglutaminase antibody seropositivity in children with type 1 diabetes mellitus.

Asian Pacific journal of allergy and immunology - 1 Jun 2017

Thammarakcharoen Thanita, Hirankarn Nattiya, Sahakitrungruang Taninee, Thongmee Thanunrat, Kuptawintu Pavinee, Kanoonthong Sriprapai, Chongsrisawat Voranush

Abstract excerpt

BACKGROUND: Patients with type 1 diabetes mellitus (T1DM) have an increased risk of celiac disease (CD). Both diseases have a common genetic susceptibility locus in the human leukocyte antigen (HLA) class II alleles. Testing for tissue transglutaminase antibodies (anti-tTG) is highly accurate for a CD diagnosis. OBJECTIVE: To determine the frequency of HLA-DQB1*0201/02 and DQB1*0302 alleles and anti-tTG...

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PMID: 27543737
DOI: 10.12932/AP0751

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