The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC.

doi:10.1038/s41467-020-15779-8

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC.

Nature communications - 30 Apr 2020

Verity Robert, Aydemir Ozkan, Brazeau Nicholas F, Watson Oliver J, Hathaway Nicholas J, Mwandagalirwa Melchior Kashamuka, Marsh Patrick W, Thwai Kyaw, Fulton Travis, Denton Madeline, Morgan Andrew P, Parr Jonathan B, Tumwebaze Patrick K, Conrad Melissa, Rosenthal Philip J, Ishengoma Deus S, Ngondi Jeremiah, Gutman Julie, Mulenga Modest, Norris Douglas E, Moss William J, Mensah Benedicta A, Myers-Hansen James L, Ghansah Anita, Tshefu Antoinette K, Ghani Azra C, Meshnick Steven R, Bailey Jeffrey A, Juliano Jonathan J

Abstract excerpt

The Democratic Republic of the Congo (DRC) harbors 11% of global malaria cases, yet little is known about the spatial and genetic structure of the parasite population in that country. We sequence 2537 Plasmodium falciparum infections, including a nationally representative population sample from DRC and samples from surrounding countries, using molecular inversion probes - a high-throughput genotyping tool. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chloroquine

Share to Democratic Republic of the Congo

Share to Drug Combinations

Share to Genome, Protozoan

Share to Malaria, Falciparum

Share to Pyrimethamine

Share to Sulfadoxine

Source

Open in PubMed Open full text

Identifiers

PMID: 32355199
DOI: 10.1038/s41467-020-15779-8
PMCID: PMC7192906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC.PMID 32355199Read ↗

Drug-Resistance and Population Structure of Plasmodium falciparum Across the Democratic Republic of Congo Using High-Throughput Molecular Inversion Probes.Semantic proximity Read ↗

Malaria drug resistance landscape in the Democratic Republic of the Congo: a spatial mapping systematic review of molecular surveillance surveysSemantic proximity Read ↗

Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probesSemantic proximity Read ↗

Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probesSemantic proximity Read ↗

High-throughput genotyping of Plasmodium vivax in the Peruvian Amazon via molecular inversion probes.Semantic proximity Read ↗

Population genomics of Plasmodium malariae from 4 African countries.Semantic proximity Read ↗

High-Throughput Genotyping of Plasmodium vivax in the Peruvian Amazon via Molecular Inversion ProbesSemantic proximity Read ↗

Mapping Plasmodium falciparum sequence variants associated with antimalarial drug resistance across populations of the Democratic Republic of Congo using ‘MOSAIC’ a high throughput methodologySemantic proximity Read ↗

Geographical Variation in Antimalarial Drug Resistance Marker Prevalence Across the Southern African Elimination Eight RegionSemantic proximity Read ↗

Understanding the Global Spread of Artemisinin Resistance: Insights from over 100K Plasmodium falciparum SamplesSemantic proximity Read ↗

Plasmodium falciparum sulfadoxine resistance is geographically and genetically clustered within the DR Congo.Semantic proximity Read ↗

Highly multiplexed ddPCR-amplicon sequencing reveals strong Plasmodium falciparum population structure and isolated populations amenable to local elimination efforts in ZanzibarSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.