Article
The orphan solute carrier SLC10A7 is a novel negative regulator of intracellular calcium signaling.
Scientific reports - 29 Apr 2020
Karakus Emre, Wannowius Marie, Müller Simon Franz, Leiting Silke, Leidolf Regina, Noppes Saskia, Oswald Stefan, Diener Martin, Geyer Joachim
Abstract excerpt
SLC10A7 represents an orphan member of the Solute Carrier Family SLC10. Recently, mutations in the human SLC10A7 gene were associated with skeletal dysplasia, amelogenesis imperfecta, and decreased bone mineral density. However, the exact molecular function of SLC10A7 and the mechanisms underlying these pathologies are still unknown. For this reason, the role of SLC10A7 on intracellular calcium signaling was...
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