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Article

Integrated analysis of DNA methylome and transcriptome identified CREB5 as a novel risk gene contributing to recurrent pregnancy loss.

EBioMedicine - 1 Sept 2018

Yu Mingming, Du Guizhen, Xu Qiaoqiao, Huang Zhenyao, Huang Xiaomin, Qin Yufeng, Han Li, Fan Yun, Zhang Yan, Han Xiumei, Jiang Ziyan, Xia Yankai, Wang Xinru, Lu Chuncheng

Abstract excerpt

BACKGROUND: Aberrant DNA methylation is considered to be a potential cause of recurrent pregnancy loss (RPL), while potential mechanism has not yet been elucidated. METHODS: In order to uncover the contribution of the perturbation of DNA methylation in RPL, we performed genome-wide DNA methylation analysis combined with genome-wide gene expression in decidua tissue. FINDINGS: Totally, 539 differentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30100398
DOI: 10.1016/j.ebiom.2018.07.042
PMCID: PMC6154871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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