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Article

Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.

PloS one - 1 Jan 2020

Hernandez-Gonzalez Ignacio, Tenorio Jair, Palomino-Doza Julian, Martinez Meñaca Amaya, Morales Ruiz Rafael, Lago-Docampo Mauro, Valverde Gomez María, Gomez Roman Javier, Enguita Valls Ana Belén, Perez-Olivares Carmen, Valverde Diana, Gil Carbonell Joan, Garrido-Lestache Rodríguez-Monte Elvira, Del Cerro Maria Jesus, Lapunzina Pablo, Escribano-Subias Pilar

Abstract excerpt

BACKGROUND: The knowledge of hereditary predisposition has changed our understanding of Pulmonary Arterial Hypertension. Genetic testing has been widely extended and the application of Pulmonary Arterial Hypertension specific gene panels has allowed its inclusion in the diagnostic workup and increase the diagnostic ratio compared to the traditional sequencing techniques. This is particularly important in the...

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Identifiers

PMID: 32348326
DOI: 10.1371/journal.pone.0232216
PMCID: PMC7190146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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