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Article

Identification of co-expressed genes associated with MLL rearrangement in pediatric acute lymphoblastic leukemia.

Bioscience reports - 29 May 2020

Zhang Hao, Liu Bei, Cheng Juan, Ma Haizhen, Li Zijian, Xi Yaming

Abstract excerpt

Rearrangements involving the mixed lineage leukemia (MLL) gene are common adverse prognostic factors of pediatric acute lymphoblastic leukemia (ALL). Even allogeneic hematopoietic stem cell transplantation does not improve the outcome of ALL cases with some types of MLL rearrangements. The aim of the present study was to identify the co-expressed genes that related to MLL rearrangement (MLL-r) and elucidate the...

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Identifiers

PMID: 32347296
DOI: 10.1042/BSR20200514
PMCID: PMC7953500

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