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Article

Correlation between NF1 genotype and imaging phenotype on whole-body MRI: NF1 radiogenomics.

Neurology - 16 Jun 2020

Liu Yunpeng, Jordan Justin T, Bredella Miriam A, Erdin Serkan, Walker James A, Vangel Mark, Harris Gordon J, Plotkin Scott R, Cai Wenli

Abstract excerpt

OBJECTIVE: To investigate the genotype-phenotype correlation between neurofibromatosis 1 (NF1) germline mutations and imaging features of neurofibromas on whole-body MRI (WBMRI) by using radiomics image analysis techniques. MATERIALS AND METHODS: Twenty-nine patients with NF1 who had known germline mutations determined by targeted next-generation sequencing were selected from a previous WBMRI study using coronal...

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Identifiers

PMID: 32345730
DOI: 10.1212/WNL.0000000000009490
PMCID: PMC7455335

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