Article
Quantitative assessment of whole-body tumor burden in adult patients with neurofibromatosis.
PloS one - 1 Jan 2012
Plotkin Scott R, Bredella Miriam A, Cai Wenli, Kassarjian Ara, Harris Gordon J, Esparza Sonia, Merker Vanessa L, Munn Lance L, Muzikansky Alona, Askenazi Manor, Nguyen Rosa, Wenzel Ralph, Mautner Victor F
Abstract excerpt
PURPOSE: Patients with neurofibromatosis 1 (NF1), NF2, and schwannomatosis are at risk for multiple nerve sheath tumors and premature mortality. Traditional magnetic resonance imaging (MRI) has limited ability to assess disease burden accurately. The aim of this study was to establish an international cohort of patients with quantified whole-body internal tumor burden and to correlate tumor burden with clinical...
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