Article
Drosophila as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system.
Proceedings of the National Academy of Sciences of the United States of America - 12 May 2020
Kim Kevin, Lane Elizabeth A, Saftien Aurelia, Wang Haiyun, Xu Yue, Wirtz-Peitz Frederik, Perrimon Norbert
Abstract excerpt
Cystic fibrosis (CF) is a recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. The most common symptoms include progressive lung disease and chronic digestive conditions. CF is the first human genetic disease to benefit from having five different species of animal models. Despite the phenotypic differences among the animal models and human CF, these models have provided...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.