Article
Natural presence of the V179D and K103R/V179D mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors in HIV-1 CRF65_cpx strains.
BMC infectious diseases - 28 Apr 2020
Liu Yongjian, Zhang Yu, Li Hanping, Wang Xiaolin, Jia Lei, Han Jingwan, Li Tianyi, Li Jingyun, Li Lin
Abstract excerpt
BACKGROUND: There is increasing evidence that HIV-1 genetic diversity can have an impact on drug resistance. The aim of this study is to investigate the epidemiological situation of CRF65_cpx and the impact of natural polymorphisms of this variant on genotypic resistance. METHODS: We used the BLAST search program followed by phylogenetic analysis to identify additional CRF65_cpx pol sequences from the Los Alamos...
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