Article
Structure and Function of Influenza Polymerase.
Cold Spring Harbor perspectives in medicine - 1 Sept 2021
Wandzik Joanna M, Kouba Tomas, Cusack Stephen
Abstract excerpt
Influenza polymerase (FluPol) plays a key role in the viral infection cycle by transcribing and replicating the viral genome. FluPol is a multifunctional, heterotrimeric enzyme with cap-binding, endonuclease, RNA-dependent RNA polymerase and polyadenylation activities. It performs its functions in the context of the viral ribonucleoprotein particle (RNP), wherein the template viral RNA is coated by multiple...
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