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Article

Progenitor Cells Activated by Platelet Lysate in Human Articular Cartilage as a Tool for Future Cartilage Engineering and Reparative Strategies.

Cells - 23 Apr 2020

Carluccio Simonetta, Martinelli Daniela, Palamà Maria Elisabetta Federica, Pereira Rui Cruz, Benelli Roberto, Guijarro Ana, Cancedda Ranieri, Gentili Chiara

Abstract excerpt

Regenerative strategies for human articular cartilage are still challenging despite the presence of resident progenitor cell population. Today, many efforts in the field of regenerative medicine focus on the use of platelet derivatives due to their ability to reactivate endogenous mechanisms supporting tissue repair. While their use in orthopedics continues, mechanisms of action and efficacy need further...

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Identifiers

PMID: 32340136
DOI: 10.3390/cells9041052
PMCID: PMC7226425

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