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Article

Age related retinal Ganglion cell susceptibility in context of autophagy deficiency

17 Apr 2020

Abstract excerpt

Abstract Glaucoma is a common age-related disease leading to progressive retinal ganglion cell (RGC) death, visual field defects and vision loss and is the second leading cause of blindness in the elderly worldwide. Mitochondrial dysfunction and impaired autophagy have been linked to glaucoma and induction of autophagy shows neuroprotective effects in glaucoma animal models. We have shown that autophagy decreases...

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PMID: 32337073
DOI: 10.1038/s41420-020-0257-4

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