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Article

The Role of Autophagy in Glaucomatous Optic Neuropathy

4 Mar 2020

Abstract excerpt

Autophagy is a conserved lysosomal-dependent pathway responsible for the degradation of cytoplasmic macromolecules. Based on the mechanism of cargo delivery to lysosomes, mammalian cells can undergo micro, macro, and chaperone-mediated autophagy. Other than physiological turnover of proteins and organelles, autophagy regulates cellular adaptation to different metabolic states and stressful conditions by allowing...

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Identifiers

PMID: 32211404
DOI: 10.3389/fcell.2020.00121

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