Article
MAPK-directed activation of the whitefly transcription factor CREB leads to P450-mediated imidacloprid resistance.
Proceedings of the National Academy of Sciences of the United States of America - 12 May 2020
Yang Xin, Deng Shun, Wei Xuegao, Yang Jing, Zhao Qiannan, Yin Cheng, Du Tianhua, Guo Zhaojiang, Xia Jixing, Yang Zezhong, Xie Wen, Wang Shaoli, Wu Qingjun, Yang Fengshan, Zhou Xuguo, Nauen Ralf, Bass Chris, Zhang Youjun
Abstract excerpt
The evolution of insect resistance to pesticides poses a continuing threat to agriculture and human health. While much is known about the proximate molecular and biochemical mechanisms that confer resistance, far less is known about the regulation of the specific genes/gene families involved, particularly by trans-acting factors such as signal-regulated transcription factors. Here we resolve in fine detail the...
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