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Long Noncoding RNAs Control the Modulation of Immune Checkpoint Molecules in Cancer

22 Apr 2020

Abstract excerpt

Long noncoding RNAs (lncRNA) that are associated with immune checkpoints have not been identified, and the mechanism by which such lncRNAs might regulate the expression of immune checkpoints is unknown in human cancer. Immune checkpoint-associated lncRNAs (ICP-lncRNA) were identified and validated via a comprehensive bioinformatic analysis of The Cancer Genome Atlas data. These ICP-lncRNAs were involved in key...

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PMID: 32321773
DOI: 10.1158/2326-6066.cir-19-0696

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