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Article

Circular RNA circ-CDYL sponges miR-1180 to elevate yes-associated protein in multiple myeloma

22 Apr 2020

Abstract excerpt

The covalently closed circular RNA has recently been proposed as a pivotal player in tumorigenesis. In the current study, we found that circ-CDYL was notably elevated in multiple myeloma tissue and plasma samples and had good diagnostic and prognostic efficacy. Functional assays showed that circ-CDYL enhanced the viability and DNA synthesis of multiple myeloma cells and inhibited apoptosis. Mechanically,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32321304
DOI: 10.1177/1535370220918191

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