Article
Human Serum Albumin Facilitates Heme-Iron Utilization by Fungi.
mBio - 21 Apr 2020
Pinsky Mariel, Roy Udita, Moshe Shilat, Weissman Ziva, Kornitzer Daniel
Abstract excerpt
A large portion of biological iron is found in the form of an iron-protoporphyrin IX complex, or heme. In the human host environment, which is exceptionally poor in free iron, heme iron, particularly from hemoglobin, constitutes a major source of iron for invading microbial pathogens. Several fungi were shown to utilize free heme, and Candida albicans, a major opportunistic pathogen, is able both to capture free...
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