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Article

Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells

1 Jan 2020

Abstract excerpt

Glioblastoma (GBM) is one of the most aggressive forms of cancer. It has been proposed that the presence within these tumors of a population of cells with stem-like features termed Glioma Initiating Cells (GICs) is responsible for the relapses that take place in the patients with this disease. Targeting this cell population is therefore an issue of great therapeutic interest in neuro-oncology. We had previously...

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PMID: 32308772
DOI: 10.7150/thno.41450

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