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Genetic and molecular features for hepadnavirus and plague infections in the Himalayan marmot

20 Apr 2020

Abstract excerpt

The Himalayan marmot (Marmota himalayana), a natural host and transmitter of plague, is also susceptible to the hepadnavirus infection. To reveal the genetic basis of the hepadnavirus susceptibility and the immune response to plague, we systematically characterized the features of immune genes in Himalayan marmot with those of human and mouse. We found that the entire major histocompatibility complex region and...

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PMID: 32308030
DOI: 10.1139/gen-2019-0161

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