Article
O-GlcNAcylation promotes malignant phenotypes of bladder cancer cells.
Neoplasma - 1 Jul 2020
Jin L, Lu M H, Dai G C, Yao Q, Xiang H, Wang L X, Xue B X, Liu X
Abstract excerpt
O-GlcNAcylation (O-GlcNAc) is a posttranslational modification that is mediated by O-GlcNAc-transferase (OGT) and reversed by O-GlcNAcase (OGA). Increasing evidence indicates that protein O-GlcNAcylation is increased in various types of cancer. In the present study, we aimed to evaluate the expression and function of both OGT and OGA in bladder cancer cells in vitro and in vivo. Expression data of OGT and OGA at...
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