Article
Blood co-expression modules identify potential modifier genes of diabetes and lung function in cystic fibrosis.
PloS one - 1 Jan 2020
Pineau Fanny, Caimmi Davide, Magalhães Milena, Fremy Enora, Mohamed Abdillah, Mely Laurent, Leroy Sylvie, Murris Marlène, Claustres Mireille, Chiron Raphael, De Sario Albertina
Abstract excerpt
Cystic fibrosis (CF) is a rare genetic disease that affects the respiratory and digestive systems. Lung disease is variable among CF patients and associated with the development of comorbidities and chronic infections. The rate of lung function deterioration depends not only on the type of mutations in CFTR, the disease-causing gene, but also on modifier genes. In the present study, we aimed to identify genes and...
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