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Article

An Integrative Transcriptomic and Metabolomic Study of Lung Function in Children With Asthma.

Chest - 1 Aug 2018

Kelly Rachel S, Chawes Bo L, Blighe Kevin, Virkud Yamini V, Croteau-Chonka Damien C, McGeachie Michael J, Clish Clary B, Bullock Kevin, Celedón Juan C, Weiss Scott T, Lasky-Su Jessica A

Abstract excerpt

BACKGROUND: Single omic analyses have provided some insight into the basis of lung function in children with asthma, but the underlying biologic pathways are still poorly understood. METHODS: Weighted gene coexpression network analysis (WGCNA) was used to identify modules of coregulated gene transcripts and metabolites in blood among 325 children with asthma from the Genetic Epidemiology of Asthma in Costa Rica...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29908154
DOI: 10.1016/j.chest.2018.05.038
PMCID: PMC6689076

Genes

ORMDL3

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