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Preimplantation loss of fertilized human ova: estimating the unobservable

22 Mar 2020

Abstract excerpt

STUDY QUESTION: What proportion of fertilized human ova are lost before implantation? SUMMARY ANSWER: An estimated 40 to 50% of fertilized ova fail to implant. WHAT IS KNOWN ALREADY: Preimplantation loss is not detectable with current technology. Published estimates of preimplantation loss range from 10 to 70%. STUDY DESIGN, SIZE, DURATION: We combine data from epidemiologic, demographic, laboratory and in vitro...

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PMID: 32296829
DOI: 10.1093/humrep/deaa048

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