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Fat mass and fat‐free mass in relation to cardiometabolic diseases: a two‐sample Mendelian randomization study

15 Apr 2020

Abstract excerpt

High body mass index is causally associated with most cardiovascular diseases but not stroke [1]. Body mass index is determined by the content of both fat mass and fat-free mass, which may have opposite effects on cardiometabolic diseases. A Mendelian randomization (MR) study that utilized 82 single-nucleotide polymorphisms (SNPs) associated with fat mass or fat-free mass index revealed that fat mass index but...

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PMID: 32294276
DOI: 10.1111/joim.13078

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