Article
Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy.
The Journal of infection - 1 Jul 2020
Benvenuto Domenico, Angeletti Silvia, Giovanetti Marta, Bianchi Martina, Pascarella Stefano, Cauda Roberto, Ciccozzi Massimo, Cassone Antonio
Abstract excerpt
BACKGROUND: SARS-CoV-2 is a new coronavirus that has spread globally, infecting more than 150000 people, and being declared pandemic by the WHO. We provide here bio-informatic, evolutionary analysis of 351 available sequences of its genome with the aim of mapping genome structural variations and the patterns of selection. METHODS: A Maximum likelihood tree has been built and selective pressure has been...
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